Prandin

Prandin is an oral antibiotic medicine used for keeping blood sugar levels under control in patients with type 2 diabetes

  • Prandin 2mg pills:

    Prandin
    $102.60
    $3.42 per item
    30 pills / 2mg
  • Prandin
    $175.20
    $2.92 per item
    60 pills / 2mg
  • Prandin
    $247.50
    $2.75 per item
    90 pills / 2mg
  • Prandin 0.5mg pills:

    Prandin
    $35.40
    $1.18 per item
    30 pills / 0.5mg
  • Prandin
    $57.00
    $0.95 per item
    60 pills / 0.5mg
  • Prandin
    $70.20
    $0.78 per item
    90 pills / 0.5mg
  • Prandin 1mg pills:

    Prandin
    $71.40
    $2.38 per item
    30 pills / 1mg
  • Prandin
    $129.00
    $2.15 per item
    60 pills / 1mg
  • Prandin
    $166.50
    $1.85 per item
    90 pills / 1mg
Product Description

What is Prandin?
Prandin or Repaglinide is an oral blood glucose lowering drug which helps control blood sugar levels in people who have type 2 diabetes. Repaglinide is the first of a new class of blood glucose lowering drugs called the ‘meglitinides’.
Prandin was previously known as Novonorm under which name it has been prescribed for many years. These drugs are aimed at controlling the surge in blood sugar levels which occurs after meals. The word ‘Prandial’ is derived from a Latin word which refers to mealtimes.

Why the name change from Novonorm to Prandin?
NovoNorm was initially manufactured by a large Danish pharmaceutical company called NovoNordisk. This company also manufactures NovoRapid, Human Mixtard, NovoMix 30 and other insulin preparations which are in widespread use. The drug is now manufactured by a different company, Sankyo, which has rebranded the drug as ‘Prandin’. The chemical compound is still called Repaglinide.

How does Prandin work?
Repaglinide is very similar to the sulphonylureas (eg. Gliclazide, Glipizide) in that it stimulates the beta cells of the pancreas to release more insulin. However, unlike the sulphonylureas, Repaglinide has to be taken before each meal. The drug has a short duration of action which concentrates it’s effect around meal time.

What is the dose of Prandin?
Prandin should be taken about half an hour before meals. It is usually taken three times a day before your three main meals. The recommended starting dose is 500 micrograms three times a day before meals. This dose is usually increased to 1 mg three times a day. The maximum recommended dose is 4 mg three to four times a day.

What happens if I forget to take a dose?
If you forget to take a dose of Prandin before a meal, you should skip this dose until the next meal. Do not take it after your meal to make up for the missed dose.

Is there anyone who should not take this medication?
Repaglinide is not recommended in children (under 18 years) or in elderly patients over the age of 75 years. You should not take this drug if you are pregnant or are breast-feeding your child.

What are the side effects of Prandin?
Abdominal pain, diarrhoea and constipation.
Prandin as with the sulphonylureas may lower blood glucose too much though this is a rare occurence. This will result in symptoms and signs of hypoglycaemia. You will feel hungry, tremulous, sweaty and dizzy. All the symptoms of hypoglycaemia are dealt with comprehensively in a separate section of this website. If these symptoms occur you should take some glucose tablets ideally, once you have checked your blood glucose levels should you have a blood glucose meter to hand.

How can I minimise the risk of these side effects?
The risk of hypoglycaemia is highest in those who skip a meal or eat very little after taking Prandin. You should never take Prandin if you do not plan to eat a meal. The risk is also raised by strenous physical exercise and excessive alcohol. You should take particular care if driving as hypoglycaemia on the road poses a risk to other road users as well as yourself.

Can Prandin be combined with other blood glucose lowering drugs?
Yes. Prandin may be combined with other drugs such as Metformin, Rosiglitazone or Pioglitazone. It should not be combined with any of the sulphonylureas such as Gliclazide, Glipizide or Glimepiride which have a very similar mode of action.

Last news:

Regulated Expression of ADAMTS Family Members in Follicles: DISCUSSION(10)

Most specifically, the results document that ADAMTS4 as well as ADAMTS1 are highly expressed in COCs before and after ovulation, suggesting that they may exert specific effects in the formation, stabilization, function (or a combination of these) of the matrix that surrounds and protects the oocyte. The elevated expression of … Continue reading

Regulated Expression of ADAMTS Family Members in Follicles: DISCUSSION(9)

Factors produced by granulosa cells that might act like heparin include versican, which has chondroitin sulfate side chains as well as the heparan sulfate proteoglycans, of which there are many, including the cell surface molecule syndecan-1. Therefore, the binding of ADAMTS1 and ADAMTS4 to these molecules likely accounts for the … Continue reading

Regulated Expression of ADAMTS Family Members in Follicles: DISCUSSION(8)

These data indicate that the COC culture system mimics some but perhaps not all events that occur in vivo, and that factors in addition to cAMP (FSH) and progesterone receptor affect expression of the ADAMTS1 gene in these murine cumulus cells. What these factors are remain to be determined.

Regulated Expression of ADAMTS Family Members in Follicles: DISCUSSION(7)

As observed in culture, the presence of cell surface proteoglycans containing heparin or chondroitin sulfate moieties may not only provide attachment sites to stabilize these proteases, but may also render them less active or inactive. That versican is tightly colocalized with hyaluronan indicates that it is localized with other hyalu-ronan-binding … Continue reading

Regulated Expression of ADAMTS Family Members in Follicles: DISCUSSION(6)

During the formation and remodeling of the COC matrix, versican, ADAMTS1, and ADAMTS4 may act in concert to permit cumulus cell migration away from the oocyte, a highly dynamic process as shown by time-lapse photography. Once expansion is complete, the high concentration of these factors in the matrix may play … Continue reading

View License File
Payment methods
Visa MasterCard American Express E-Check Automated Clearing House